Atrial Fibrillation

Matthew Capowski

Administrator
Staff member
#1
This thread will be used to organize information about atrial fibrillation.

Medscape has an unusually insightful article for a mainstream medical publication titled Atrial Fibrillation Care: Put the Catheter (and Rx Pad) Down: http://www.medscape.com/viewarticle/842739?src=sttwit

A group of researchers in Adelaide have shown—first in animal models[1,2] and now in humans [3,4]—that promoting basic health dramatically improves AF burden. Their methods and results have taught us how AF happens. Although work remains, it is clear that lifestyle diseases, via pressure- and volume-induced atrial stretch, inflammation, or neural imbalances, induce disease in and around the cells of the heart.

The coolest part about these data are that treatment of lifestyle diseases—mostly, the removal of excesses—not only reduces AF burden but also improves the structure of the heart. Even fibrosis (aka scar) can regress, which is a novel way to think about cardiac biology.
 

Matthew Capowski

Administrator
Staff member
#4
This 2010 study concludes that "Diabetes was associated with higher risk of developing atrial fibrillation, and risk was higher with longer duration of treated diabetes and worse glycemic control." This leads one to wonder if managing metabolic syndrome is not also a way to treat or prevent atrial fibrillation.

Diabetes Mellitus, Glycemic Control, and Risk of Atrial Fibrillation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896589/